Risk factors

Conditions or disorders that may increase the risk of pulmonary valve stenosis include:

• German measles (rubella). Having German measles (rubella) during pregnancy increases the risk of pulmonary valve stenosis in the baby.
• Noonan syndrome. This genetic disorder causes various problems with the heart's structure and function.
• Rheumatic fever. This complication of strep throat can cause permanent damage to the heart, including the heart valves. It can increase the risk of developing pulmonary valve stenosis later in life.
• Carcinoid syndrome. A rare cancerous tumor releases certain chemicals into the bloodstream, causing shortness of breath, flushing and other signs and symptoms. Some people with this syndrome develop carcinoid heart disease, which damages heart valves.